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The Makerere University and University of California, San Francisco (MU-UCSF ) Research Collaboration

The mission of the MU-UCSF Research Collaboration is to 1) conduct high-quality research in infectious diseases; 2) build capacity through training; and 3) strengthen infrastructure to help integrate research into policy by linking researchers and policy makers. In 1998, the MU-UCSF Research Collaboration focused on characterizing the efficacy of new antimalarial therapies, defining new public health approaches to malaria and understanding the evolution of antimalarial drug resistance in urban and rural Ugandan settings. In 2004, MU and UCSF investigators began studying other infectious diseases including HIV and TB.


To date, the scientists of the MU-UCSF Research Collaboration have conducted malaria and TB surveillance of over 750,000 patients throughout Uganda; have gained extensive experience in clinical and translational research; developed sophisticated laboratories for cutting edge research in immunology, drug and parasite resistance; and a have an impressive track record of developing and overseeing rigorously conducted clinical trials in Uganda having enrolled over 7500 participants, including IND studies. The MU-UCSF Research Collaboration conducts clinical trials and laboratory research in Kampala, Tororo, Mbale, Jinja, and Mbarara and supports surveillance programs and cohort studies throughout Uganda at government health facilities. The collaboration has also sought advice and worked with the Ugandan Ministry of Health and variety of Ugandan country partners to ensure that the research programs are harmonized with local priorities.


The MU-UCSF Research Collaboration has produced over 150 publications, many of which had Ugandan or US trainees as first authors. In addition, the MU-UCSF Collaboration has trained 31 Ugandan researchers in degree accredited programs at UCSF, MU, UC Berkeley and the London School of Hygiene and Tropical Medicine and over 30 UCSF medical students, fellows and post-docs at UCSF.