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    •     Resistance of Malaria     Parasites to     Artemisinin-Based     Combination Therapies
    •      Translational studies of      antimalarial drug resistance
    • Training in Malaria Research in Uganda
    • Pharmacokinetics of Piperaquine and Lumefantrine in Young Children in Tororo Uganda
    • Pharmacokinetic Interactions between Antiretroviral Agents, Lopinavir/Ritonavir and Efavirenz and Antimalarial Drug Combinations, Artesunate/ Amodiaquine and Artemether/Lumefantrine
    Past Projects
    • U01
    • Pharmacokinetics of Antimalarial Medications in Ugandan Children
    Junior investigator / student / trainee / fellow projects
    • Effect of TS prophylaxis on placental malaria
    • Prevalence and evolution of HIV drug resistance in Ugandan children receiving ART
    • HIV subtype and tropism as a predictor of HIV disease progression
    • children
Translational studies of antimalarial drug resistance

Funded by:  Doris Duke Charitable Foundation
from Dec 2004 to Dec 2010


Major goals:

    1. Assessment of associations between the complexity and diversity of malaria infections and treatment outcomes.
    2. Characterization of the selection of drug resistant malaria parasites.
    3. Determination of molecular mechanisms of antimalarial drug resistance.
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MU-UCSF Research Collaboration