Parasite Resistence - Publications

1. Baliraine FN, Rosenthal PJ. Prolonged selection of pfmdr1 polymorphisms after treatment of falciparum malaria with artemether-lumefantrine in Uganda. J Infect Dis. 204:1120-4, 2011.

2. Baliraine FN, Nsobya SL, Achan J, Tibenderana JK, Talisuna AO, Greenhouse B, Rosenthal PJ. Limited ability of Plasmodium falciparum pfcrt, pfmdr1, and pfnhe1 polymorphisms to predict quinine in vitro sensitivity or clinical effectiveness in Uganda. Antimicrob Agents Chemother. 55:615-22, 2011.

3. Nsobya SL, Kiggundu M, Nanyunja S, Joloba M, Greenhouse B, Rosenthal PJ. In vitro sensitivities of Plasmodium falciparum to different antimalarial drugs in Uganda. Antimicrob Agents Chemother, 54:1200-6, 2010.

4. Nawaz F, Nsobya SL, Kiggundu M, Joloba M, Rosenthal PJ. Selection of parasites with diminished drug susceptibility by amodiaquine-containing antimalarial regimens in Uganda. J Infect Dis. 2009 Dec; 200(11):1650-7.

5. Nsobya SL, Kiggundu M, Joloba M, Dorsey G, Rosenthal PJ. Complexity of Plasmodium falciparum clinical samples from Uganda during short-term culture J Infect Dis. 2008 Nov 15;198(10):1554-7

6. Nsobya, SL, Dokomajilar, C, Joloba, M, et al. Resistance-mediating Plasmodium falciparum pfcrt and pfmdr1 alleles after treatment with artesunate-amodiaquine in Uganda. Antimicrob Agents Chemother, 2007;51(8), 3023-5.

7. Dokomajilar C, Nsobya SL, Greenhouse B, Rosenthal PJ, Dorsey G. Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine from a highly endemic area of Uganda. Antimicrobial Agents and Chemotherapeutics May 2006;1893-1895.

8. Francis D, Nsobya SL, Talisuna A, Yeka A, Kamya MR, Machekano R, Dokomajilar C, Rosenthal PJ, Dorsey G. Geographic differences in antimalarial drug efficacy explained by differences in endemicity and not molecular markers of drug resistance. Journal of Infectious Diseases 2006;193(7):978-86.

9. Nsobya SL, Parikh S, Kironde F, Lubega G, Kamya MR, Rosenthal PJ, Dorsey, G. Molecular evaluation of the Natural of History of Asymptomatic parasitemia in Ugandan Children. J Infect Dis. 2004 Jun 15;189(12):2220-6.

10. Dorsey G, Dokomajilar C, Kiggundu M, Staedke SG, Kamya MR, Rosenthal PJ. Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda. American Journal of Tropical Medicine and Hygiene 2004;71(6):758-63.

11. Staedke SG, Sendagire H, Lamola S, Kamya MR, Dorsey G, Rosenthal PJ. Relationship between age, molecular markers, and response to sulfadoxine-pyrimethamine treatment in Kampala, Uganda. Tropical Medicine and International Health 2004;9(5):624-9.

12. Kyabayinze D, Cattamanchi A, Kamya MR, Rosenthal PJ, Dorsey G. Validation of a simplified method for using molecular markers to predict sulfadoxine-pyrimethamine treatment failure in African children with falciparum malaria. American Journal of Tropical Medicine and Hygiene 2003;69:247-52.

13. Dorsey G, Kamya MR, Singh AJ, Rosenthal PJ. Polymorphisms in Plasmodium falciparum pfcrt and pfmdr-1 genes and in vivo chloroquine resistance in Kampala, Uganda. Journal of Infectious Diseases 2001;183:1417-20.